Study overview
Overview
- Study title
- Maternal antecedents of adiposity and studying the transgenerational role of hyperglycemia and insulin (MAASTHI)
- Study link
- https://maasthi.com/
- Participants enrolled
- 4,862
- Lead institute
- Indian Institute of Public Health-Bengaluru (IIPH-B)
- Principal investigator (PI)
- Giridhara R Babu (PHFI)
- Principal investigator profile
- Open profile
- Study design
- Prospective
- Location
- Karnataka (Bengaluru)
- Single / multiple sites
- Single Site
- Key highlights
- MAASTHI is a cohort study in the public health facilities in Bangalore, India. The study follows pregnant women since 2016 to prospectively assess the effects of glucose levels in pregnancy on the risk of adverse infant outcomes, especially in predicting the possible risk markers of later chronic diseases.The primary objective of the study is to investigate the effect of glucose levels in pregnancy on skinfold thickness (adiposity) in infancy as a marker of future obesity and diabetes in offspring.
- Reference paper 1
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5065083/
- Reference paper 2
- https://doi.org/10.1136/bmjopen-2022-063794
Insights & criteria
Insights
- Inclusion criteria
- Pregnant Women (14-36 weeks)
- Exclusion criteria
- Having major co-existing diseases as HIV/ADIS, hepatitis B, diabetes and Inability to complete the oral glucose tolerance test (OGTT)
- Socio‑demographic / economic
- Lower socioeconomic strata
- Recruitment and timeline
- April 2016-June 2019
- Follow‑up
- Follow-up at Birth, 14 weeks, 1 year, 2 years, 3 years
- Keywords
- Maternal Health, Birth, Non Communicable disease
Details
Details
- Age group
- 18-45 years
- Gender
- Women
- Scope
- National
- Category
- Birth and Maternal Cohort